Measurement of particulate matter concentration from dust storms and its relationship with interleukin 6 in healthy individuals in Zahedan

Background & Aim: Dust storms have detrimental effects on human health, the environment and the economy. Epidemiological research shows an association between air pollution and increased mortality from cardiovascular complications. Interleukins play key roles in production of inflammatory responses. The aim of this study was to determine the relationship between PM10 and interleukin 6 in healthy individuals in Zahedan. Methods: This study was conducted from March 2017 to October 2018. According to the climatic and geographical characteristics of Zahedan city, 4 stations were determined and sampled by environmental sampling once every 6 days, as well as on dusty days and the concentration of PM10 was measured. Also, in different conditions (clean air and polluted air conditions), the rate of interleukin 6 changes in the blood samples of 40 volunteers aged 18 to 30 years was evaluated by ELISA method. Results: The mean concentration of PM10 air during 7 months of study was 205.65 μg/m3. Therefore, PM10 as one of the main air pollutants in most days of this study were higher than the standard. Also, interleukin 6 plasma levels in air pollution conditions were significantly higher than the control group (P <0.05). Conclusion: Due to the exacerbation of cardiovascular and respiratory diseases at a time when the concentration of Particulate matter exceeds the standard, it is important to pay attention to health and personal care programs.